HEPL

Elementary knowledge of epidemiological statistics. Anatomy and physiology of main functions. Notions in pathologic physiology related to main systems. Analytical principles connected with different types of assays.

To have a critical approach the results of the analyses. To know to analyze causes of a process out control. To be able to denounce drifts of analytical quality involving rejection of biological results. To prove of logic and initiative.

Theory interpretation of biological data at analytic, semiological and pathologic-physiological levels and about normal values.

Glucide metabolism: pathogenesis and complications near diabetic end; biological exploration and therapeutic balance tests; assays.

Lipid metabolism: serum lipidic compounds; normal metabolism; pathologic states; apoproteins; exploration tests.

Protein metabolism: serum protein properties; physico-chemical and biological properties of main specific plasmatic proteins.

Calcium and phosphorus function exploration: hormonal regulations; pathologic states; assays.

Enzymatic functional exploration: effects of physico-chemicals parameters on enzymatic reaction; serum enzyme semiology; isoenzymes; asays.

Renal function tests: homeostatic principles, investigation methods.

Thyroid exploration: biochemistry and mode of action of thyroid hormones; assays.

Liver function tests: pathologic states including viral hepatitis; tests.

Cellular receptors: classification; internalization; pathologic states.

Tumors markers: classification; semiology.

Acid-basis equilibrium and blood gazes

Clinical biology laboratories accreditation.

BOREL J.P., Biochimie dynamique, Ed. Maloine, 1987

MARTIN D.W., Précis de Biochimie de Harper, Presses de l'Université Laval, Editions ESKA, 1985

RAWN J.D., Ed., Traité de Biochimie, De Boeck-Wesmael, 1990

WEINMAN S., La Biochimie de Lubert-Stryer, 3e Ed., Flammarion Médecine Sciences, 1992